What is Repatha® (evolocumab) and what is it used for?

Repatha® is a medicine that lowers levels of ‘bad’ cholesterol (LDL-C), a type of fat, in the blood.

Repatha® contains the active substance evolocumab, a monoclonal antibody (a type of specialised protein designed to attach to a target substance in the body).

Evolocumab is designed to attach to a substance called PCSK9 that affects the liver’s ability to take in cholesterol. By attaching to, and mopping up PCSK9, the medicine increases the amount of cholesterol entering the liver and so lowers the level of cholesterol in the blood.

Repatha® is used in patients who cannot currently control their cholesterol levels with diet and medication.

What is Repatha used for

You should stay on your cholesterol-lowering diet while taking this medicine. Repatha® may be used with other medicines that lower your levels of cholesterol.